Human transitional and IgM low mature naïve B cells preserve permissive B‐cell receptors
نویسندگان
چکیده
منابع مشابه
IgD attenuates the IgM-induced anergy response in transitional and mature B cells
Self-tolerance by clonal anergy of B cells is marked by an increase in IgD and decrease in IgM antigen receptor surface expression, yet the function of IgD on anergic cells is obscure. Here we define the RNA landscape of the in vivo anergy response, comprising 220 induced sequences including a core set of 97. Failure to co-express IgD with IgM decreases overall expression of receptors for self-...
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ژورنال
عنوان ژورنال: Immunology & Cell Biology
سال: 2021
ISSN: 0818-9641,1440-1711
DOI: 10.1111/imcb.12478